Project Example
Monoclonal Antibody Purification Process Optimization
Concuir’s consultants significantly improved the overall equipment effectiveness (OEE) of one client’s large scale monoclonal antibody purification process. We helped our client achieve these feats by addressing O-ring failures in the slurry nozzles, introducing variable height chromatography, and increasing the team’s proficiency in handling columns through training.
All the training we provided enabled our client’s in-house team to pack columns properly and efficiently in a repeatable manner, confidently test column packing quality, perform and interpret height equivalent to a theoretical plate (HETP) and asymmetry calculations, and enforce proper preventative maintenance procedures. The training not only aided in significantly improving OEE, but also reduced their in-house team’s column packing time by 70%, greatly enhancing team efficiency in production.
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More Project Examples by Concuir
Filtration Process Scale-Up
A client asked our team to perform a scale up of their current filtration process for a drug product.
Redeveloped Existing CIP Cycles
In order to meet quality and validation requirements, Concuir assessed and subsequently redeveloped a client’s existing cleaning-in-place (CIP) cycle.
Partnering for Global Launch Success
We partner with pharma companies launching in the US, Canada, Europe, and globally, guiding therapies from strategy through commercialization.